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Bacterial and Mammalian cell culture

The biologics portfolio includes products that are produced using production hosts ranging from microbial to mammalian systems

The microbial derived biologics have a large cost-advantage and faster production cycles. The protein products are generally trapped intracellular and devoid of most post translational modifications. Due to this reason the microbial systems are ideal for the production of hormones such as insulin, cytokines and growth factors such as GCSF, interferons and partial antibody structures such as Fab fragments

Mammalian production systems on the other hand ensure product secretion and efficient post-translational processing that closely mimics the natural synthesis of complex biologics such as erythropoietin and monoclonal antibodies

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